ketofol for bone marrow aspiration and lumbar puncture in children with all

نویسندگان

azam sadat hashemi department of pediatrics, hematology, oncology and genetics research center, shahid sadoughi university of medical scien

vida ayatolahi department of surgery, shahid sadoughi university of medical sciences and health services, yazd, iranسازمان اصلی تایید شده: دانشگاه علوم پزشکی شهید صدوقی یزد (shahid sadooghi university of medical sciences)

rozita ghilian department of internal medicine. hematology oncology and genetics research center shahid sadoughi university of medicalسازمان اصلی تایید شده: دانشگاه علوم پزشکی شهید صدوقی یزد (shahid sadooghi university of medical sciences)

ali ghadami yazdi department of surgery, shahid sadoughi university of medical sciences and health services, yazd, iran.سازمان اصلی تایید شده: دانشگاه علوم پزشکی شهید صدوقی یزد (shahid sadooghi university of medical sciences)

چکیده

abstract background ketofol is usually using as a sedative drug during painful procedures now. that provides sedation, analgesia and rapid recovery. the aim of this study was to compare the efficacy, respiratory and hemodynamic profiles, and side effects of two various combination of ketamine and propofol in patients undergoing bone marrow aspiration (bma) and lumbar puncture (lp). materials and methods this randomized, double blinded study was designed to compare the quality of analgesia and side effects of intravenous ketofol in sixty boys and girls. in this study patients received a slow bolus injection of a solution containing combination of equal amount of propofol and ketamine (1:1) (group i) or two parts of propofol plus one part of ketamine (2:1) (group ii). subsequent slow bolus injects to a predetermined sedation level using ramsay sedation scale. vital signs, oxygen saturation (spo2) and incidence of any side effects were recorded. results ketofol was used in 49 surgical procedures in children with a median age of 5 years (1 to 10 years old). in this study there was an increase postoperative nausea, psychomimetic side effects, and increase recovery time with the largest ketamine dosage (group i). (p-value< 0.001) conclusion the adjunctive use of smaller dose of ketamine in ketofol combination minimizes the psychomimetic side effects and shortens the recovery time. a large number of patients are required to evaluate and validate these findings.

برای دانلود باید عضویت طلایی داشته باشید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Ketofol for bone marrow aspiration and lumbar puncture in Children with ALL

Abstract Background Ketofol is usually using as a sedative drug during painful procedures now. That Provides sedation, analgesia and rapid recovery. The aim of this study was to compare the efficacy, respiratory and hemodynamic profiles, and side effects of two various combination of ketamine and propofol in patients undergoing bone marrow aspiration (BMA) and lumbar puncture (LP). Materials...

متن کامل

General Anesthesia for Lumbar Puncture and Bone Marrow Aspiration /Biopsy in Children with Cancer

Abstract Background Multiple procedures (Lumbar puncture and bone marrow aspiration /biopsy) cause pain, stress, depression and etc for the patients and their families. Various methods have been recommended for pain reduction during invasive procedures. The aim of this study is to report the complications following general anesthesia. Materials and Methods In this prospective observational ...

متن کامل

General Anesthesia for Lumbar Puncture and Bone Marrow Aspiration /Biopsy in Children

Background  Multiple procedures (Lumbar puncture and bone marrow aspiration /biopsy) cause pain, stress, depression and etc for the patients and their families. Various methods have been recommended for pain reduction during invasive procedures. The aim of this study is to report the complications following general anesthesia. Methods In this prospective observational study, two hundred and ...

متن کامل

general anesthesia for lumbar puncture and bone marrow aspiration /biopsy in children

background  multiple procedures (lumbar puncture and bone marrow aspiration /biopsy) cause pain, stress, depression and etc for the patients and their families. various methods have been recommended for pain reduction during invasive procedures. the aim of this study is to report the complications following general anesthesia. methods in this prospective observational study, two hundred and two...

متن کامل

General Anesthesia for Lumbar Puncture and Bone Marrow Aspiration /Biopsy in Children with Cancer

BACKGROUND Multiple procedures (Lumbar puncture and bone marrow aspiration /biopsy) cause pain, stress, depression and etc for the patients and their families. Various methods have been recommended for pain reduction during invasive procedures. The aim of this study is to report the complications following general anesthesia. MATERIALS AND METHODS In this prospective observational study, two ...

متن کامل

Effect of two Different Concentrations of Propofol and Ketamine Combinations (Ketofol) in Pediatric Patients under Lumbar Puncture or Bone Marrow Aspiration

Abstract Background Ketamine is an anesthetic drug that is importantly analgesic without respiratory depression. Ketamine increases blood pressure and heart rate. Propofol is an anesthetic drug with good sedation, rapid recovery, but it causes respiratory depression, low heart rate and low blood pressure. Combination of Ketamine and Propofol provides sedation, analgesia and rapid recovery wit...

متن کامل

منابع من

با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید


عنوان ژورنال:
iranian journal of pediatric hematology and oncology

جلد ۱، شماره ۴، صفحات ۱۲۶-۱۳۲

کلمات کلیدی

میزبانی شده توسط پلتفرم ابری doprax.com

copyright © 2015-2023